The stunning actress was named as the ambassador for Saks’ Annual Key to the Cure shopping event, which, along with the Breast Cancer Research Foundation, has raised more than $33 million for the fight against the disease in the past 12 years.

Uma said: “Everyone I know has been affected by breast cancer one way or the other. It is vital that we work toward a cure as well as develop more accurate and advance testing.”

Uma will star in print adverts as well as a national public service announcement, in which she will wear a limited-edition T-shirt designed by Donna Karan.

All proceeds from the $35 top will be donated to local partner charities and the designer wanted to do her bit to help.

She said: “For me, it’s not just about dressing women; it’s about addressing the issues that are so important to all of us.”

The T-shirts will be available at all Saks Fifth Avenue stores and on Saks.com from October.